Meet Myx

Superbugs evolve. So does our cure.

Myx is a machine that evolves a patient-matched phage against a drug-resistant infection and makes the dose on site.

↳ Move your cursor. The bacteria scatter, the phage keep hunting.

The Myx instrument: a benchtop machine that evolves and produces a patient-matched phage on site.
01 · The problem

Drug-resistant infections are winning.

SINCE YOU OPENED THIS PAGE
0

people worldwide have died of a drug-resistant infection. That is about one every 25 seconds.

NEXT IN 25s · BASED ON 1.27M DEATHS/YR (LANCET)
35,000
U.S. deaths a year (CDC)
1.27M
deaths worldwide a year (Lancet)
Nearly dry.
The state of the antibiotic pipeline.

The two tools we have run into the same wall.

02 · Why today’s answers fall short

A fixed drug can’t keep up with an infection that keeps changing.

ILLUSTRATIVE
ANTIBIOTICS

The drug works until the bacteria change.

An antibiotic knocks the infection back. Resistant survivors regrow, and the same drug no longer works. Bacteria evolve resistance faster than new drugs arrive, and few are coming.

Watch the full arms race in the Story

That is the problem Myx was built to solve.

03 · Our solution

A patient-matched phage, evolved and produced on site.

Three steps run inside one instrument, from the patient’s isolate to the matched dose.

The future of evolution
The software

Every run, measured on screen.

Each run is one patient and one infection, tracked from the first round of selection to a sequenced, release-tested dose.

reef · evolution run · case 0412
Case 0412 · K. pneumoniae · carbapenem-resistant 6 rounds
STRAIN
KPC+resistance
patientisolate
ANCESTOR
PB-1047phage bank
nearmatch
RESULT
EOP 0.60evolved
0.00ancestral
Arms race over rounds
the evolving phage overtakes the resistant host and drives it to extinction; the untreated twin keeps climbing
resistant bacteriaevolving phageuntreated
0123456crossover · round 3clearedrounds of selection →
evolved phage · 6 rounds
Crossoverround 3
Bacteria clearedround 5
EOP, evolved0.60
EOP, ancestral0.00
arms race over 6 rounds of selection
04 · Why it wins

Better medicine, and a business built to reach patients.

01Regulatory

We start where the bar is lower.

We begin with topical rare-disease indications, where the regulatory bar is lower and there is more than one route to the FDA.

02IP

We own clean freedom to operate.

We evolve the phage rather than engineer it, so the work stays clear of the engineered-phage patents and the path to the clinic stays ours.

03Economics

Made where the patient is.

One instrument runs evolve, match and produce on site, turning a manual craft practiced at a few specialist centers into something a hospital can run.

04Market

A need the pipeline can’t meet.

Resistance keeps rising while few new antibiotics are coming. A therapy that adapts to each infection does not run out the way a fixed drug does.

Onboarding early partners

Bring us the infection nothing else can treat.

Clinicians, hospitals, investors, and advisors each have a path. Tell us where you fit and we will take it from there.

CliniciansHospitalsInvestorsAdvisors